kirazmattson
846 posts
Apr 22, 2026
10:16 PM
|
Fildena 100 mg (which contains sildenafil citrate), nitric oxide (NO) is the starting signal that makes the whole erection pathway work. Here’s how it fits into the mechanism: When a person is sexually stimulated, nerve endings in the penis release nitric oxide (NO). This molecule acts like a chemical messenger that tells the surrounding smooth muscle cells to relax. NO then activates an enzyme called guanylate cyclase, which increases levels of cyclic guanosine monophosphate (cGMP). cGMP is the key substance that relaxes smooth muscles in penile blood vessels, allowing more blood to flow in—resulting in an erection. Now where Fildena 100 Mg comes in: Sildenafil (in Fildena) is a PDE5 inhibitor PDE5 is the enzyme that breaks down cGMP By blocking PDE5, Fildena prevents cGMP from being destroyed too quickly So the role of nitric oxide is fundamental: it initiates the production of cGMP, and Fildena enhances and prolongs the effect of that NO-triggered cGMP signal.
|
