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Forum > Why avoid grapefruit with Fildena Super Active?
Why avoid grapefruit with Fildena Super Active?
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Oct 30, 2025
11:45 PM
Fildena Super Active is a medication used to treat erectile dysfunction (ED), containing Sildenafil Citrate in an orally disintegrating form for faster action. While effective, certain dietary interactions can impact its safety and effectiveness—one of the most important being grapefruit and grapefruit juice.

Grapefruit contains compounds called furanocoumarins, which can inhibit the CYP3A4 enzyme in the liver. This enzyme is responsible for metabolizing Sildenafil in the body. When CYP3A4 is blocked, Sildenafil levels can rise dramatically, increasing the risk of side effects such as headache, dizziness, flushing, low blood pressure, and vision disturbances. In severe cases, it may lead to dangerous complications like irregular heartbeat or fainting.

Even small amounts of grapefruit can affect drug metabolism, so it’s best to completely avoid grapefruit and related citrus fruits while taking FILDENA SUPER ACTIVE. Other citrus or supplements that interact with liver enzymes should also be discussed with a doctor.

By following these precautions, patients can maximize the safety and effectiveness of Fildena Super Active, ensuring reliable erectile support without unnecessary risks. Proper medical guidance and attention to diet are key to achieving the best results.


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