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Forum > How does Malegra 200 affect the levels of nitric o
How does Malegra 200 affect the levels of nitric o
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cliffordfosterr
Guest
Jan 28, 2025
3:40 AM
Malegra 200 is a brand of sildenafil, which is commonly used to treat erectile dysfunction. Sildenafil works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5). By blocking this enzyme, Malegra 200 mg increases the levels of cyclic guanosine monophosphate (cGMP), which plays a key role in regulating blood flow in the body. When cGMP levels rise, they cause the smooth muscles in blood vessels to relax, allowing more blood to flow into the penis during sexual arousal, thus facilitating an erection. Nitric oxide (NO) is a molecule that also plays a central role in this process, as it stimulates the production of cGMP. Sildenafil doesn’t directly increase nitric oxide levels but rather amplifies the effects of nitric oxide by preventing the breakdown of cGMP. Essentially, the presence of nitric oxide enhances the action of sildenafil, making it more effective in promoting blood flow and improving erectile function. So, while Malegra 200 doesn't directly increase nitric oxide levels, it works in synergy with nitric oxide to produce its effects.


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