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Guest
Nov 28, 2023
4:16 AM
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Malegra 200 is a medication primarily used for the treatment of erectile dysfunction (ED) in men. It contains sildenafil citrate, which is the same active ingredient found in the well-known ED medication Viagra. Sildenafil citrate belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Understanding how Malegra 200 works involves grasping its mechanism of action and its effects on the body.
Erectile dysfunction occurs when there's insufficient blood flow to the penis, making it difficult to achieve or maintain an erection firm enough for sexual activity. Malegra 200, through its active ingredient sildenafil citrate, works by inhibiting the action of the enzyme PDE5. This enzyme breaks down a chemical called cyclic guanosine monophosphate (cGMP), which is responsible for relaxing the smooth muscles and dilating the blood vessels in the penis. When PDE5 is inhibited by sildenafil citrate, the levels of cGMP increase, promoting increased blood flow into the penis during sexual stimulation. This enhanced blood flow helps in achieving and sustaining an erection.
The medication doesn't automatically induce an erection; sexual arousal is necessary to stimulate the release of nitric oxide in the erectile tissue. Nitric oxide, in turn, activates an enzyme that produces cGMP, which relaxes the blood vessels in the penis and allows blood to flow in, creating an erection. Malegra 200 assists this natural process by amplifying the effects of nitric oxide through the inhibition of PDE5.
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