Poxet-30 blocks the reuptake of serotonin from the synapse, which is the gap between nerve cells across which chemical messages are sent from one nerve cell to another. If the re-uptake of serotonin by the first nerve cell (pre-synaptic) is blocked, this means that there is more serotonin remaining for the receiving nerve cell (post-synaptic), which allows nerve cells to communicate with each other for longer selective serotonin reuptake inhibitor (SSRI) that is used specifically for premature ejaculation (PE), as it has a rapid onset of action, with maximum effect within 1-2 hours and a short half-life, which means that it is rapidly eliminated from the body within 24 hours. Ejaculation is a reflex that is mediated by the sympathetic nervous system.